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Myostatin Boy EssayM any(prenominal) scientists believe the find could eventually pass away to drugs for treating eople with tendinous dystrophy and other pass-destroying conditions. And athletes would near surely want to get their hands on much(prenominal)(prenominal) a drug and use it like steroids to bulk up. The male childs mutant DNA segment was found to hold back production of a protein called myostatin that limits muscle growth. The news comes seven years after researchers at Johns Hopkins University in Baltimore created buffer storage mighty mice by turning false the gene that directs cells to produce myostatin. Now we can say that myostatin acts the aforementioned(prenominal) way in humans as in animals, give tongue to the boys physician, Dr. Markus Schuelke, a professor in the shaver neurology department at Charite/ University Medical Center Berlin. We can apply that knowledge to humans, including trial therapies for muscular dystrophy. Given the huge pot ential market for such drugs, researchers at universities and pharmaceutical companies already are attempt to find a way to limit the amount and activity of myostatin in the body. Wyeth has Just begun human tests of a genetically engineered antibody designed to neutralize myostatin.Dr. Lou Kunkel, director of the genomics program at Boston Childrens Hospital and professor of pedology and genetics at Harvard Medical School, said success is possible within several years. Just fall this protein by 20, 30, 50 percent can have a profound effect on muscle bulk, said Kunkel, who is among the doctors participating in the Wyeth research. Slow wasting process Muscular dystrophy is the worlds most crude genetic disease. There is no cure and the most common form, Duchennes, usually kills before adulthood.The few treatments universe tried to soggy its progression have serious side effects. Muscle asting also is common in the elderly and patients with diseases such as cancer and AIDS. If yo u could find a way to block myostatin activity, you might slow the wasting process, said Dr. Se-Jin Lee, the Johns Hopkins professor whose team created the mighty mice. Lee said he believes a myostatin blocker also could suppress go accumulation and thus thwart the development of diabetes. Lee and Johns Hopkins would receive royalties for any myostatin-blocking drug made by Wyeth.Dr. Eric Hoffman, director of Childrens National Medical Centers Research Center for Genetic Medicine, said he believes a muscular dystrophy cure will be found, but he is fainthearted whether it will be a myostatin-blocking drug, another treatment or a combination, because about a twelve genes have some effect on muscles. He said a mystotatin- blocking drug could attend other groups of people, including astronauts and others who lose muscle mass during long stints in zero gravity or when immobilized by illness or a broken limb. Eventual health problems?Researchers would not disclose the German boys i ndividuality but said he was born to a nd three other close male relatives all were unusually strong, with one of them a construction worker able to unload heavy curbstones by hand. In the mother, one copy of the gene is mutated and the other is normal the boy has two mutated copies. One almost definitely came from his father, but no information about him has been disclosed. The mutation is very rare in people. The boy is healthy now, but doctors worry he could eventually suffer heart or other health problems.In the past few years, scientists have seen great potential in myostatin-blocking strategies. Internet marketers have been vendition myostatin-blocking supplements to bodybuilders, though doctors say the products are useless and perhaps dangerous. Some researchers are trying to turn off the myostatin gene in chickens to produce more meat per bird. And several breeds of cattle have natural variations in the gene that, aided by selective breeding, give them far more muscle and l ess fat than other steer. He could do the iron cross when he was 5 months old, said his adoptive mother, Dana Hoekstra of Roosevelt Park.She was referring to a difficult gymnastics move in hich a male athlete suspends himself by his arms amongst two pause rings, forming the shape of a cross. Liam has the kind of physical attributes that bodybuilders and other athletes dream about 40 percent more muscle mass than normal, Jaw-dropping strength, breathtaking quickness, a speedy metabolism and almost no body fat. Liam can run like the wind, has the agility of a cat, lifts pieces of furniture that most children his age couldnt weigh across a slick floor and eats like there is no tomorrow without gaining weight.Liam Hoekstra was hanging upside down by his feet when he performed an inverted sit-up, his shirt falling away to expose flux abdominal muscles. It was a display of raw power one might expect to see from an prodigious gymnast. Liam is 19 months old. The so-called myostatin blo ckade has generated tremendous interest in the bodybuilding community. Some nutritional supplements call option to block myostatin, but researchers have said the claims are not scientifically valid. If the myostatin protein is knocked out, muscles grow and rejuvenate much more uickly,